Osteoarthritis (OA) is a complex “whole joint” disease. Knee pain is the most disabling symptom due to inflammatory process, lack of lubricating fluid along with “wear and tear of cartilage and soft tissue in the knee joint.

For the knee OA, intraarticular (IA) injection (corticosteroids, viscosupplements, blood-derived products) is preferred as the last nonoperative modality, if the other conservative treatment modalities are ineffective.

IA corticosteroid injectionshelp to reduce inflammation and provide short term reduction in OA pain and can be considered as an adjunct to core treatment for the relief of moderate to severe pain in people with OA.

IA hyaluronic acid (HA) injectionsincrease lubrication in joint and also provide nutrition to the cartilage.

Recently studies indicate some role ofIA platelet rich plasma injections are promising for relieving pain, improving knee function and quality of life, especially in younger patients, and in mild OA cases. The current literature and our experience indicate that IA injections are safe and have positive effects for patient satisfaction.